产品说明
一般描述
IgG (Immunoglobulin G) antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Rabbit anti-dog IgG is isolated by affinity isolation and conjugated to Fluorescein Isothiocyanate (FITC).
The variable region of IgG antibody is specific to antigens and is highly conserved. IgG has four subclasses- IgG1, IgG2a, IgG2b and IgG2c.
特异性
Anti-Dog IgG (whole molecule)-FITC antibody is specific for dog IgG subclasses.
免疫原
Purified dog IgG
应用
Anti-Dog IgG (whole molecule)-FITC antibody may be used for direct immunofluorescence using dog peripheral blood lymphocytes at a minimum working dilution of 1:32.
生化/生理作用
IgG (Immunoglobulin G) antibody provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections. IgG antibody has its function similar to IgM antibody in complement system activation. IgG participates in hypersensitivity type II and type III. It helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.
外形
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.
储存及稳定性
For continuous use, store at 2-8 ℃ for up to one month.
For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing, or storage in "frost-free" freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
MDL编号 | MFCD00221535 |
NACRES | NA.46 |
产品性质
生物来源 | rabbit |
质量水平 | 200 |
偶联物 | FITC conjugate |
抗体形式 | affinity isolated antibody |
antibody product type | secondary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
储存条件 | protect from light |
technique(s) | direct immunofluorescence: 1:32 |
储存温度 | −20℃ |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | nwg |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
Sigma-Aldrich