您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 品牌 > Sigma-Aldrich > 4′-(甲硫基)苯乙酮

4′-(Methylthio)acetophenone

4′-(甲硫基)苯乙酮

品牌
Sigma-Aldrich
CAS
1778-09-2
货号
396583
包装型号
规格纯度
97%
参考价格
254.08 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
1778-09-2
4′-(Methylthio)acetophenone
4′-(甲硫基)苯乙酮
产品介绍:

产品说明

一般描述

4′-(Methylthio)acetophenone (4-(Methylthio)acetophenone, p-(methylthio) acetophenone, 4-MTAP) is a sulphur containing organic building block. It is a key intermediate in drug synthesis. Its industrial preparation, via Friedel-Crafts acylation reaction in the presence of aluminium chloride as catalyst and acetyl chloride as acylating agent has been reported. It has been prepared by the acetylation reaction of thioanisole with acetic anhydride in the presence of solid acid catalyst.

应用

4′-(Methylthio)acetophenone may be used for the synthesis of Vioxx (Rofecoxib), an non-steroidal anti-inflammatory drug (NSAID). It may be used in the synthesis of (E)-1-[4-(methylsulfanyl)phenyl]-3-phenylprop-2-en-1-one.

包装

1 g in glass bottle

基本信息

线性分子式CH3SC6H4COCH3
分子量166.24
EC 号217-213-1
MDL编号MFCD00039835
PubChem化学物质编号24864677
NACRESNA.22

产品性质

质量水平100
测定97%
mp80-82 ℃ (lit.)
SMILES stringCSc1ccc(cc1)C(C)=O
InChI1S/C9H10OS/c1-7(10)8-3-5-9(11-2)6-4-8/h3-6H,1-2H3
InChI keyJECUZQLBQKNEMW-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves

Sigma-Aldrich

推荐产品