6-（二甲氨基）嘌呤

产品名称：

938-55-6
6-(Dimethylamino)purine
6-DMAP
N⁶,N⁶-Dimethyladenine
6-（二甲氨基）嘌呤
N⁶,N⁶-二甲腺嘌呤

产品介绍：

产品说明

一般描述

6-(Dimethylamino)purine (6-DMAP) is a purine-based metabolite with two condensed heterocyclic rings and two methyl groups linked to the amino group of the purine unit of adenine.

应用

6-(Dimethylamino)purine has been used:

as a supplement in GR-1 aa medium (bovine medium) for parthenogenetic activation of bovine oocytes to study its potential for embryo development
in the activation step during the production of nuclear transfer embryos
as a supplement in HCR2aa medium to activate interspecies embryos derived from interspecies somatic cell nuclear transfer (iSCNT) technique

包装

100, 250, 500 mg in poly bottle
1 g in poly bottle

生化/生理作用

6-(Dimethylamino)purine (6-DMAP) is a protein kinase and cyclin-dependent kinase inhibitor. It acts as a secondary metabolite and mediates RNA modification. 6-DMAP is a potent cytokinetic inhibitor and is used in parthenogenesis and meiosis studies. It is also used to promote pronuclei formation in mammalian oocytes. 6-DMAP is a dual fluorescence molecule according to femtosecond fluorescence up-conversion spectroscopy studies.

其他说明

斯克里普斯代谢组学和质谱技术中心独立生成的串联质谱数据可在PDF D2629.pdf 中查看或下载。斯克里普斯代谢物组学和质谱技术中心的METLIN代谢物数据库中有测试代谢物。要了解更多信息，请访问sigma.com/metlin。

基本信息

经验(实验)分子式	C₇H₉N₅
分子量	163.18
Beilstein	7634
EC 号	213-344-3
MDL编号	MFCD00005573
PubChem化学物质编号	24893701

产品性质

生物来源	synthetic (organic)
质量水平	100
测定	≥98%
形式	powder
mp	259-262 ℃ (lit.)
溶解性	water: 50 mg/mL, clear to hazy, colorless to light yellow
储存温度	−20℃
SMILES string	CN(C)c1ncnc2[nH]cnc12
InChI	1S/C7H9N5/c1-12(2)7-5-6(9-3-8-5)10-4-11-7/h3-4H,1-2H3,(H,8,9,10,11)
InChI key	BVIAOQMSVZHOJM-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)