产品说明
应用
Palmitoyl-DL-carnitine chloride has been used to study its effect on inflammatory cytokines and calcium (Ca2+) influx, using in vitro models of prostate cancer.
包装
100 mg in poly bottle
1 g in poly bottle
生化/生理作用
Palmitoyl-DL-carnitine chloride is known to inhibit biofilm formation mediated by Pseudomonas aeruginosa and Escherichia coli. It is a phosphokinase C inhibitor.
Long-chain acylcarnitine and well-known intermediate in mitochondrial fatty acid oxidation. Modifies myocardial levels of high-energy phosphates and free fatty acids in the heart. Increases erythroid colony formation in culture. Reduces surface negative charge of erythrocytes and myocytes. Reported to affect currents and inhibit endothelium-dependent relaxation induced by acetylcholine and substance P in a dose dependent manner by suppressing the intracellular calcium signal transduction in endothelial cells.
基本信息
| 线性分子式 | C23H46NO4 · Cl |
| 分子量 | 436.07 |
| MDL编号 | MFCD00063481 |
| PubChem化学物质编号 | 24278634 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 200 |
| 生物来源 | synthetic (organic) |
| 测定 | ≥98% (TLC) |
| 形式 | powder |
| 颜色 | white |
| 溶解性 | H2O: 25 mg/mL (with heat or sonication) |
| 储存温度 | −20℃ |
| SMILES string | Cl.CCCCCCCCCCCCCCCC(=O)OC(CC(O)=O)C[N](C)(C)C |
| InChI | 1S/C23H46NO4.ClH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(27)28-21(19-22(25)26)20-24(2,3)4;/h21H,5-20H2,1-4H3,(H,25,26);1H |
| InChI key | LGVBWSFTXDIBPB-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
