Amastatin hydrochloride hydrate

产品名称：

100938-10-1
Amastatin hydrochloride hydrate
(2S,3R)-3-Amino-2-hydroxy-5-methylhexanoyl-Val-Val-Asp hydrochloride hydrate

产品介绍：

产品说明

一般描述

Chemical structure: peptide

生化/生理作用

It inhibits cytosolic leucine aminopeptidase (EC.3.4.11.1), microsomal aminopeptidase M (EC.3.4.11.2) and bacterial leucine aminopeptidase (EC.3.4.11.10). It is less effective against aminopeptidase A (EC 3.4.11.7), the enzyme that converts angiotensin II to angiotensin III. Potentiates the CNS effects of vasopressin and oxytocin in vivo.
Effective concentration: 1-10 μM.

基本信息

经验(实验)分子式	C₂₁H₃₈N₄O₈ · HCl · xH₂O
分子量	511.01 (anhydrous basis)
Beilstein	8888370
MDL编号	MFCD00150636
PubChem化学物质编号	24890521

产品性质

质量水平	200
生物来源	synthetic (organic)
测定	≥97% (HPLC)
形式	powder
mp	202-205 ℃
溶解性	methanol: 1 mM (Stock solution stable for 1 month at −20 ℃. Working solution stable for 1 day.)
作用机制	enzyme \| inhibits
抗生素抗菌谱	neoplastics
储存温度	−20℃
SMILES string	Cl[H].[H]O[H].CC(C)C[C@@H](N)[C@H](O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O
InChI	1S/C21H38N4O8.ClH.H2O/c1-9(2)7-12(22)17(28)20(31)25-16(11(5)6)19(30)24-15(10(3)4)18(29)23-13(21(32)33)8-14(26)27;;/h9-13,15-17,28H,7-8,22H2,1-6H3,(H,23,29)(H,24,30)(H,25,31)(H,26,27)(H,32,33);1H;1H2/t12-,13+,15+,16+,17+;;/m1../s1
InChI key	WBYDQJQQTMJMQH-AFROIDPFSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)