产品说明
一般描述
Chemical structure: peptide
生化/生理作用
It inhibits cytosolic leucine aminopeptidase (EC.3.4.11.1), microsomal aminopeptidase M (EC.3.4.11.2) and bacterial leucine aminopeptidase (EC.3.4.11.10). It is less effective against aminopeptidase A (EC 3.4.11.7), the enzyme that converts angiotensin II to angiotensin III. Potentiates the CNS effects of vasopressin and oxytocin in vivo.
Effective concentration: 1-10 μM.
基本信息
| 经验(实验)分子式 | C21H38N4O8 · HCl · xH2O |
| 分子量 | 511.01 (anhydrous basis) |
| Beilstein | 8888370 |
| MDL编号 | MFCD00150636 |
| PubChem化学物质编号 | 24890521 |
产品性质
| 质量水平 | 200 |
| 生物来源 | synthetic (organic) |
| 测定 | ≥97% (HPLC) |
| 形式 | powder |
| mp | 202-205 ℃ |
| 溶解性 | methanol: 1 mM (Stock solution stable for 1 month at −20 ℃. Working solution stable for 1 day.) |
| 作用机制 | enzyme | inhibits |
| 抗生素抗菌谱 | neoplastics |
| 储存温度 | −20℃ |
| SMILES string | Cl[H].[H]O[H].CC(C)C[C@@H](N)[C@H](O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O |
| InChI | 1S/C21H38N4O8.ClH.H2O/c1-9(2)7-12(22)17(28)20(31)25-16(11(5)6)19(30)24-15(10(3)4)18(29)23-13(21(32)33)8-14(26)27;;/h9-13,15-17,28H,7-8,22H2,1-6H3,(H,23,29)(H,24,30)(H,25,31)(H,26,27)(H,32,33);1H;1H2/t12-,13+,15+,16+,17+;;/m1../s1 |
| InChI key | WBYDQJQQTMJMQH-AFROIDPFSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
