产品说明
应用
Aconitase may be usefull in diabetes research as well as to study structural conservation between iron-responsive element binding proteins (IRE-BP) and isomerases .
包装
150, 250 mg in serum bottle
生化/生理作用
Aconitase catalyses the stereo-specific isomerization of citrate to isocitrate via cis-aconitate in the tricarboxylic acid cycle. Aconitase is inhibited by cyanide, sulfide and copper and mercury at low concentrations. It is competitively inhibited by trans-aconitate. Aconitase contains an internal Fe-S cluster which is responsible for its activity.
单位定义
One unit will convert 1.0 μmole of citrate (via cis-aconitate) to isocitrate per min at pH 7.4 at 25 ℃.
分析说明
Crude preparation containing aconitase activity
基本信息
酶学委员会(EC)编号 | 4.2.1.3 ( BRENDA | IUBMB ) |
MDL编号 | MFCD00130335 |
NACRES | NA.54 |
产品性质
质量水平 | 200 |
形式 | solid |
分子量 | ~66 kDa by gel filtration |
储存温度 | −20℃ |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich