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位置:首页 > 品牌 > Sigma-Aldrich > Leupeptin, Hemisulfate, Microbial-CAS 103476-89-7-Calbiochem
产品名称:
103476-89-7
Leupeptin, Hemisulfate, Microbial-CAS 103476-89-7-Calbiochem
Ac-LLR-CHO, 1/2H2SO4
产品介绍:

产品说明

一般描述

A reversible inhibitor of trypsin-like proteases and cysteine proteases. Also known to inhibit activation-induced programmed cell death and to restore defective immune responses of HIV+ donors. Also available as a 50 mM solution in H2O (Cat. No. 509281).
A reversible inhibitor of trypsin-like proteases and cysteine proteases. Also known to inhibit activation-induced programmed cell death and to restore defective immune response in HIV+ donors. Often used for the inhibition of endoproteinase Lys-C, kallikrein, papain, plasmin, thrombin, cathepsin B, and trypsin. Leupeptin does not inhibit chymotrypsin, elastase, renin, or pepsin. The recommended working range is 10-100 µM for most applications.

包装

50 mg in Glass bottle
100 mg in Plastic ampoule
5, 10, 25 mg in Plastic ampoule

生化/生理作用

Product does not compete with ATP.
Primary Target
trypsin- and cysteine-like proteases
Reversible: yes
Cell permeable: no

警告

Toxicity: Standard Handling (A)

序列

Ac-Leu-Leu-arginal, hemisulfate

重悬

Following reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Aqueous stock solutions are stable for up to 1 week at 4°C or for up to 1 month at -20°C.

其他说明

Montenez, J.P., et al. 1994. Toxicol. Lett. 73, 201.
Sarin, A., et al. 1994. J. Immunol.153, 862.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C20H38N6O4 · 0.5H2SO4
分子量475.59
MDL编号MFCD00037012

产品性质

质量水平200
测定≥90% (HPLC)
形式lyophilized solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
desiccated (hygroscopic)
颜色 white
溶解性water: 50 mg/mL
运输ambient
储存温度−20℃
InChI1S/C20H38N6O4/c1-12(2)9-16(24-14(5)28)19(30)26-17(10-13(3)4)18(29)25-15(11-27)7-6-8-23-20(21)22/h11-13,15-17H,6-10H2,1-5H3,(H,24,28)(H,25,29)(H,26,30)(H4,21,22,23)/p+1/t15-,16-,17-/m0/s1
InChI keyGDBQQVLCIARPGH-ULQDDVLXSA-O

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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