Anti-NOS3 (Ab-1177) antibody produced in rabbit

产品说明

一般描述

NOS3 (nitric oxide synthase 3) is located on human chromosome 7q36.

免疫原

Peptide sequence around aa. 1175-1179 (T-Q-S-F-S), according to the protein NOS3.

应用

Anti-NOS3 (Ab-1177) antibody has been used in western blotting.

生化/生理作用

Modifications in the NOS3 (nitric oxide synthase 3) gene leads to erectile dysfunction susceptibility, age of onset and severity. In heart, NOS3 helps in NO (nitric oxide) synthesis. It also controls vascular tone and blood pressure.

特点和优势

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目标描述

Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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