产品说明
一般描述
Immunoglobulin G (IgG) has a primary structure with heavy and light chains. Disulfide bonds link the two heavy chains, the heavy and light chains and resides inside the chains. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4 with different heavy chains, named γ1, γ2, γ3, and γ4, respectively. Limited digestion using papain cleaves the antibody into three fragments, two of which are identical and contain the antigen-binding activity. The third fragment does not possess antigen-binding activity and is known as fragment crystallizable (Fc). It interacts with cells and effector molecules. The Fc fragment contains the CH2 and CH3 domains of the antibody molecule. Maternal IgG is the only antibody transported across the placenta to the fetus. It passively immunizes the infants.
特异性
This product was prepared from monospecific antiserum by immunoaffinity chromatography using Rabbit IgG coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Donkey Serum, Rabbit IgG, Rabbit IgG F(c) and Rabbit Serum. No reaction was observed against Rabbit IgG F(ab′)2.
免疫原
Rabbit IgG F(c) fragment
物理属性
Antibody format: IgG
外形
Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
重悬
Reconstitute with 1.0 mL deionized water (or equivalent).
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.46 |
产品性质
| 质量水平 | 100 |
| 生物来源 | donkey |
| 偶联物 | rhodamine conjugate |
| 抗体形式 | affinity isolated antibody |
| antibody product type | secondary antibodies |
| 克隆 | polyclonal |
| 形式 | lyophilized powder |
| species reactivity | rabbit |
| technique(s) | indirect ELISA: suitable indirect immunofluorescence: suitable |
| 运输 | wet ice |
| 储存温度 | 2-8℃ |
安全信息
| 象形图 |   |
| 警示用语： | Danger |
| 危险声明 | H302 - H311 - H411 |
| 预防措施声明 | P280 - P301 + P312 + P330 - P302 + P352 + P312 |
| 危险分类 | Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2 |
| 补充剂危害 | EUH032 |
| 储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
