Anti-Nitric Oxide Synthase, Brain (251-270) antibody produced in rabbit

产品说明

一般描述

Nitric Oxide Synthase, Brain (NOS1) is mapped to human chromosome 12q24.22. The NOS isoform found in neurons is a 150 kDa protein. It is also termed as brain NOS (bNOS). Human bNOS and endothelial NOS (eNOS) share 52% amino acid identity, and rat and human bNOS share 93% amino acid identity.

免疫原

synthetic peptide corresponding to nitric oxide synthase (NOS) of rat brain origin (bNOS, amino acids 251-270) conjugated to KLH. The immunogen sequence is highly conserved in human bNOS.

应用

Anti-Nitric Oxide Synthase, Brain (251-270) antibody produced in rabbit has been used in:

• double immunolabelling,
• immunofluorescence
• western blotting

生化/生理作用

Nitric Oxide Synthase, Brain (bNOS) is present also in skeletal muscle, where it is complexed with dystrophin and is absent in Duchenne muscular dystrophy (DMD). Neuronal and endothelial NOS are constitutively expressed and are dependent on Ca²⁺ calmodulin for nitric oxide (NO) production.

外形

0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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