产品说明
生化/生理作用
LCK (proto-oncogene) belongs to the Src family of kinase and is mainly expressed in T cells. It is important for T cell development and homeostasis. LCK is upregulated in acute and chronic leukemias, colorectal and prostate cancers.
Tyrosine kinase that activates T-lymphocytes.
外形
Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
法律信息
PRECISIO is a registered trademark of sigma-aldrich Co. LLC
基本信息
| MDL编号 | MFCD03457310 |
| NACRES | NA.32 |
产品性质
| 质量水平 | 200 |
| 重组 | expressed in baculovirus infected Sf9 cells |
| 产品线 | PRECISIO® Kinase |
| 测定 | ≥70% (SDS-PAGE) |
| 形式 | buffered aqueous glycerol solution |
| specific activity | 180-244 nmol/min·mg |
| 分子量 | ~84 kDa |
| UniProt登记号 | P06239 |
| 运输 | dry ice |
| 储存温度 | −70℃ |
| Gene Information | human ... LCK(3932) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter |
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