您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 品牌 > Sigma-Aldrich > 人类BNDF脑源性营养因子配体ELISA试剂盒

Human Fas Ligand ELISA Kit

人类BNDF脑源性营养因子配体ELISA试剂盒

品牌
Sigma-Aldrich
货号
RAB0178
规格纯度
for serum, plasma, and cell culture supernatants
参考价格
7209.4 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Human Fas Ligand ELISA Kit
FasL
人类BNDF脑源性营养因子配体ELISA试剂盒
产品介绍:

产品说明

一般描述

The Human Fas Ligand ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human Fas Ligand in serum, plasma, cell culture supernatants and urine.

免疫原

Recombinant Human Fas Ligand

应用

请参考Protocol了解详情。

生化/生理作用

Binding of Fas Ligand (FasL) to Fas receptor triggers apoptosis in Fas-bearing cells. FasL has the ability to kill T cells and activate B cells which leads to down-regulation of the immune response. The mechanism of Fas induced apoptosis involves recruitment of pro-caspase 8 through an adaptor molecule called FADD (Fas-associated protein with death domain) followed by processing of the pro-enzyme to active forms. These active caspases then cleave various cellular substrates leading to eventual cell death. FasL is also involved in AGE (advanced glycation end-product)-mediated apoptosis in human retinal ARPE-19 cells, suggesting its role in diabetic retinopathy. Changes in the activity of FasL suppress normal apoptosis, leading to abnormal survival and growth of tumor cells. Mutations in the FasL gene causes autoimmune lymphoproliferative syndrome (ALPS).

其他说明

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

基本信息

NACRESNA.32

产品性质

species reactivityhuman
包装kit of 96 wells (12 strips x 8 wells)
technique(s)ELISA: suitable
capture ELISA: suitable
inputsample type plasma
sample type cell culture supernatant(s)
sample type serum
assay rangeinter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 2 pg/mL
standard curve range: 1.37-1000 pg/mL
detection methodcolorimetric
运输wet ice
储存温度−20℃
Gene Informationhuman ... FASLG(356)

组份列表

组份可单独销售

货号组份
RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)
RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)
RABSTOP3ELISA Stop Solution (Item I)
RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
RABWASH420X Wash Buffer (Item B)

安全信息

象形图GHS05
警示用语:Warning
危险声明H290
预防措施声明P234 - P390
危险分类Met. Corr. 1
储存分类代码8A - Combustible, corrosive hazardous materials
WGKWGK 3

Sigma-Aldrich

推荐产品