产品说明
一般描述
Tubulin is one of several members of a small family of globular proteins which polymerize to form cytoskeletal structures called microtubules. The most common members of the tubulin family are α-tubulin and β-tubulin. Tubulin dimers, typically composed of α- and β-tubulin subunits, assemble onto microtubules forming large polymers. β-III tubulin is a unique microtubule subunit that is found expressed almost exclusively in neurons. Due to the unique expression pattern of β-III tubulin it is often utilized as a marker to identify neuronal cells from other brain cells such as glia which do not express it. β-III tubulin also serves as a cytoarchitectural marker since it is primarily found within neurite extensions.
特异性
This antibody recognizes Beta III Tubulin.
免疫原
Synthetic linear peptide corresponding to human Beta III Tubulin.
应用
Research Sub Category
Neurofilament & Neuron Metabolism
Research Category
Neuroscience
Immunohistochemistry: Representive lot has been shown to work in adult mouse brain.
质量
Evaluated by Immunocytochemistry in rat E18 cortex cells.
Immunocytochemistry Analysis: A 1:400 dilution of this antibody detected Beta III Tubulin in rat E18 cortex cells.
目标描述
50 kDa calculated
外形
Affinity purified
Purified rabbit polyclonal conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
Rat E18 cortex cells
法律信息
ALEXA FLUOR is a registered trademark of Life Technologies
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | ALEXA FLUOR® 488 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
species reactivity | mouse, rat |
species reactivity (predicted by homology) | human (based on 100% sequence homology) |
technique(s) | immunocytochemistry: suitable immunohistochemistry: suitable |
NCBI登记号 | NP_006077 |
UniProt登记号 | Q13509 |
运输 | wet ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich