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Anti-TLS Antibody, clone 1FU-1D2

品牌
Sigma-Aldrich
货号
04-1552
规格纯度
ascites fluid, clone 1FU-1D2, from mouse
参考价格
6022.61 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-TLS Antibody, clone 1FU-1D2
75 kDa DNA-pairing protein, FUS-CHOP fusion protein, FUS-CHOP protein fusion, Fusion gene in myxoid liposarcoma, Oncogene FUS, Oncogene TLS, Translocated in liposarcoma protein, fus-like protein, fus/tls-chop oncogene, fusion (involved in t(12, 16) in ma
产品介绍:

产品说明

一般描述

The TLS/FUS protein contains an RNA-recognition motif and is a component of nuclear riboprotein complexes. It resembles a transcription factor in that it binds DNA, contributes a transcriptional activation domain to the FUS-ERG oncoprotein, and interacts with several transcription factors in vitro. It binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. It may play a role in maintenance of genomic integrity.

特异性

This antibody recognizes TLS.

免疫原

Linear peptide corresponding to human TLS.
Epitope: Unknown

应用

Research Sub Category
RNA Metabolism & Binding Proteins

Transcription Factors
Use Anti-TLS Antibody, clone 1FU-1D2 (Mouse Monoclonal Antibody) validated in WB, ICC to detect TLS also known as 75 kDa DNA-pairing protein, FUS-CHOP fusion protein.
Immunocytochemistry Analysis:
1:500 dilution from a representative lot detected TLS in C2C12 cells.
Research Category
Epigenetics & Nuclear Function

Epigenetics & Nuclear Function

质量

Evaluated by Western Blot in HepG2 cell lysate.
Western Blot Analysis: 1:1,000 dilution of this antibody detected TLS on 10 µg of HepG2 cell lysate.

目标描述

Observed at 65 kDa

外形

Unpurified
Unpurified mouse monoclonal IgG1κ preservative-free ascites.

储存及稳定性

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

分析说明

Control
HepG2 cell lysate

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源mouse
抗体形式ascites fluid
antibody product typeprimary antibodies
克隆1FU-1D2, monoclonal
species reactivityhuman, mouse, rat
technique(s)immunocytochemistry: suitable
western blot: suitable
同位素/亚型IgG1κ
NCBI登记号NP_004951.1
UniProt登记号P35637
运输dry ice
Gene Informationhuman ... FUS(2521)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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