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位置:首页 > 品牌 > Sigma-Aldrich > Anti-Neurofilament 200kDa Antibody, clone NE14, Alexa Fluor® 555 Conjugate

Anti-Neurofilament 200kDa Antibody, clone NE14, Alexa Fluor® 555 Conjugate

品牌
Sigma-Aldrich
货号
MAB5256A5
规格纯度
clone NE14, from mouse, ALEXA FLUOR® 555
参考价格
7029.8 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Neurofilament 200kDa Antibody, clone NE14, Alexa Fluor® 555 Conjugate
Neurofilament heavy polypeptide, NF-H, 200 kDa neurofilament protein, Neurofilament triplet H protein
产品介绍:

产品说明

一般描述

Neurofilaments are a type of intermediate filament that serve as major elements of the cytoskeleton supporting the axon cytoplasm. They are the most abundant fibrillar components of the axon, being on average 3-10 times more frequent than axonal microtubules. Neurofilaments (10nm in dia.) are built from three intertwined protofibrils which are themselves composed of two tetrameric protofilament complexs of monomeric proteins. The neurofilament triplet proteins (68/70, 160, and 200 kDa) occur in both the central and peripheral nervous system and are usually neuron specific. The 68/70 kDa NF-L protein can self-assemble into a filamentous structure, however the 160 kDa NF-M and 200 kDa NF-H proteins require the presence of the 68/70 kDa NF-L protein to co-assemble. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas and neuroblastomas stain positively for neurofilaments. Although typically restricted to neurons, neurofilaments have been detected in paragangliomas and adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilaments. For more neurofilament information and epitope maps, search "neurofilament" on our website.

应用

Detect Neurofilament 200kDa using this Anti-Neurofilament 200kDa Antibody, clone NE14, Alexa Fluor 555 Conjugate validated for use in ICC & IHC.

质量

Evaluated by Immunocytochemistry in rat E18 primary cortex cells.
Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Neurofilament in rat E18 primary cortex cells.

外形

Protein A purified

其他说明

Unconjugated Anti-Neurofilament has been shown to work with multiple species including Human and Porcine.

法律信息

ALEXA FLUOR is a registered trademark of Life Technologies

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源mouse
偶联物ALEXA FLUOR® 555
抗体形式purified antibody
antibody product typeprimary antibodies
克隆NE14, monoclonal
species reactivityrat, mouse, pig
species reactivity (predicted by homology)human (100% sequence homology), porcine (immunogen homology)
technique(s)immunocytochemistry: suitable
immunohistochemistry: suitable
同位素/亚型IgG1
NCBI登记号NP_066554
UniProt登记号P12036
运输wet ice

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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