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Gabapentin-CAS 60142-96-3-Calbiochem

品牌
Sigma-Aldrich
CAS
60142-96-3
货号
5.08506
规格纯度
A water soluble GABA analog that interacts with voltage-gated calcium channels in cortical neurons.
参考价格
1516.72 *本价格含增值税费
促销
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数量
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产品名称:
60142-96-3
Gabapentin-CAS 60142-96-3-Calbiochem
L-type Voltage Gated Ca2+ Channel Blocke, Gabapentin
产品介绍:

产品说明

一般描述

A water soluble GABA analog originally developed to treat epilepsy and neuropathic pain but is not believed to act on the same brain receptors. Gabapentin interacts with voltage-gated calcium channels in cortical neurons. It binds to the α2δ subunit (1 and 2) and has been found to reduce calcium currents after chronic but not acute application via an effect on trafficking of voltage-dependent calcium channels in the central nervous system.

生化/生理作用

Primary Target
α2δ subunit of L-type voltage gated Ca2+ channels

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Eroglu, C. et al. 2009. Cell.139, 380.
Hendrich, J. et al. 2008. Proc. Natl. Acad. Sci. USA105, 3628.
Davies, A. et al. 2007. Trends Pharmacol. Sci.28, 220.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C9H17NO2
分子量171.24
MDL编号MFCD00865286

产品性质

质量水平100
测定≥98% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
颜色 white
溶解性water: 100 mM
储存温度2-8℃
InChI1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12)
InChI keyUGJMXCAKCUNAIE-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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