产品说明
一般描述
Purmorphamine is a cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells.
A cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells (EC50 = 1 µM) and in MC3T3-E1 lineage-committed preosteoblasts. Also shown to induce transdifferentiation in pre-adipocytes and myoblasts. Its effects are reported to be synergistic with bone morphogenetic protein-4 (BMP-4). Reported to induce osteogenesis by activation of the Hedgehog signaling pathway.
包装
5 mg in Plastic ampoule
Packaged under inert gas
应用
InSolution
警告
Toxicity: Irritant (B)
外形
A 50 mM (5 mg/192 µl) solution of Purmorphamine (Cat. No. 540220) in DMSO.
重悬
Following initial thaw, aliquot and freeze (-20°C).
其他说明
Wu, X., et al. 2004. Chem. Biol.11, 1229.
Wu, X., et al. 2002. J. Am. Chem. Soc.124, 14520.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | liquid |
manufacturer/tradename | Calbiochem® |
储存条件 | OK to freeze desiccated (hygroscopic) protect from light |
储存温度 | −20℃ |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H341 |
预防措施声明 | P201 - P202 - P280 - P308 + P313 - P405 - P501 |
危险分类 | Muta. 2 |
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 2 |
闪点(F) | 188.6 °F |
闪点(C) | 87 ℃ |
Sigma-Aldrich