产品说明
一般描述
Cell-permeable adenylate cyclase inhibitor. Blocks PTH-stimulation of adenylate cyclase (IC50 = 200 µM). Reduces PGE2-induced inhibition of O2·– production.
包装
5 mg in Glass bottle
生化/生理作用
Cell permeable: yes
Target IC50: 200 µM against adenylate cyclase
Product does not compete with ATP.
Reversible: no
Primary Target
adenylate cyclase
警告
Toxicity: Irritant (B)
重悬
Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 2 weeks at 4°C.
其他说明
Talpain, E., et al. 1995. Br. J. Pharmacol. 114, 1459.
Tamaoki, J., et al. 1993. Prostaglandins45, 363.
Fabbri, E., et al. 1991. J. Enzyme Inhib.5, 87.
Goldsmith, B.A. and Abrams, T.W. 1991. Proc. Natl. Acad. Sci. USA 88, 9021.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C9H11N5O |
| 分子量 | 205.22 |
| MDL编号 | MFCD00210216 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | solid |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze |
| 颜色 | off-white |
| 溶解性 | DMSO: 25 mg/mL water: 5 mg/mL |
| 运输 | ambient |
| 储存温度 | 2-8℃ |
| InChI | 1S/C9H11N5O/c10-8-7-9(12-4-11-8)14(5-13-7)6-2-1-3-15-6/h4-6H,1-3H2,(H2,10,11,12) |
| InChI key | UKHMZCMKHPHFOT-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
