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位置:首页 > 品牌 > Sigma-Aldrich > COX-2 Inhibitor V, FK3311-CAS 116686-15-8-Calbiochem

COX-2 Inhibitor V, FK3311-CAS 116686-15-8-Calbiochem

品牌
Sigma-Aldrich
CAS
116686-15-8
货号
236015
规格纯度
The COX-2 Inhibitor V, FK3311, also referenced under CAS 116686-15-8, controls the biological activity of COX-2. This small molecule/inhibitor is primarily used for Cell Signaling applications.
参考价格
3352.28 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
116686-15-8
COX-2 Inhibitor V, FK3311-CAS 116686-15-8-Calbiochem
4'-Acetyl-2'-(2,4-Difluorophenoxy)methanesulfonanilide
产品介绍:

产品说明

一般描述

A cell-permeable and orally available sulfonanilide that acts as a COX-2-selective non-steroidal anti-inflammatory drug (NSAID). Shown to exhibit 500-fold greater potency in inhibiting the LPS-induced (IC50 = 316 nM in human mononuclear cells) than the non-induced/constitutive (IC50 = 160 µM in human platelets) TxB2 production in vitro and effectively alleviate warm ischemia-reperfusion injury in the canine liver and rat lung in vivo.

包装

5 mg in Glass bottle
Packaged under inert gas

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他说明

Otani, Y., et al. 2007. J. Invest. Surg.20, 175.
Sunose, Y., et al. 2001. Transplant Proc.33, 862.
Grossman, C.J., et al. 1995. Inflamm. Res.44, 253.
Nakamura, K., et al. 1993. Chem. Pharm. Bull.41, 2050.
Tsuji, K., et al. 1992. Chem. Pharm. Bull.40, 2399.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C15H13F2NO4S
分子量341.33

产品性质

质量水平100
测定≥98% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
颜色 white
溶解性ethanol: 15 mg/mL
DMSO: 30 mg/mL
运输ambient
储存温度2-8℃
InChI1S/C15H13F2NO4S/c1-9(19)10-3-5-13(18-23(2,20)21)15(7-10)22-14-6-4-11(16)8-12(14)17/h3-8,18H,1-2H3
InChI keyDIIYLGZNZGPXRR-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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