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Dipeptidyl Peptidase IV Inhibitor I

二肽基肽酶 IV 抑制剂 I

品牌
Sigma-Aldrich
货号
D3822
包装型号
规格纯度
参考价格
2835.05 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Dipeptidyl Peptidase IV Inhibitor I
Diprotin A
二肽基肽酶 IV 抑制剂 I
双蛋白 A
产品介绍:

产品说明

生化/生理作用

Dipeptidyl peptidase IV is a key enzyme involved in the regulation of incretin hormone levels in the gastrointestinal tract. Incretin hormones, such as glucagon like peptide (GLP-1) and glucose-dependent insulinotopic hormone (GIP) / gastoric inhibitory peptide, cause the glucose stimulated release of insulin. This allows the endocrine system to preemptively stimulate release insulin in response to ingestion of high sugar foods. Type 2 diabetics demonstrate a greatly reduced incretin induced insulin release response. This response in hyperglycemic conditions is counterbalanced by the rapid rate of degradation of these incretin hormones by dipeptidyl peptidase IV in normal conditions. Inhibition of dipeptidyl peptidase IV results in longer lifetime of the incretin hormones in the GI tract and thus prolonged stimulation of insulin production. Specific dipeptidyl peptidase inhibitors are actively being explored as drug targets for treating type 2 diabetes and several candidates are actively in clinical trial. Dipeptidyl peptidase IV (Diprotin A) inhibits both endo- and exopeptidase activities of Dipeptidyl peptidase IV.

序列

Ile-Pro-Ile

基本信息

经验(实验)分子式C17H31N3O4
分子量341.45
NACRESNA.77

产品性质

质量水平200
测定≥95% (HPLC)
形式solid
颜色 white
储存温度2-8℃

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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