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Monoclonal Anti-CXCR-1 (IL-8 RA) antibody produced in mouse

品牌
Sigma-Aldrich
货号
C6223
规格纯度
clone 42705.111, purified immunoglobulin, lyophilized powder
参考价格
4731.57 *本价格含增值税费
促销
服务
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  • 增值税票
数量
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产品名称:
Monoclonal Anti-CXCR-1 (IL-8 RA) antibody produced in mouse
产品介绍:

产品说明

一般描述

Chemokine receptor CXCR1 also refers as type I IL-8 receptor or IL-8RA is a class A, rhodopsin-like G-protein-coupled receptor, expressed mainly in neutrophils but not in T or B lymphocytes . It has a crucial role in cellular signal transduction and targeted as drug receptors. Monoclonal anti-CXCR-1 (IL-8 RA) antibody can be used to neutralize the bioactivity facilitated by human cell surface CXCR-1. Mouse anti-CXCR-1 (IL-8 RA) antibody reacts specifically with CXCR-1 transfected cells but not with the parent cell line. The product has also shown no cross-reactivity with human CXCR-2.

特异性

The antiboody, in the presence of anti-CXCR2 (Sigma Product No. C6348), will neutralize human cell surface CXCR-1 mediated-myloperoxidase release from human granulocytes induced by IL-8. The antibody reacts with human CXCR1 transfectant cells and not the parent cell line. The antibody shows no cross-reactivity with CXCR2.

免疫原

human CXCR1 transfected NSO mouse myeloma cells.

应用

Monoclonal anti-CXCR-1 (IL-8 RA) antibody can be used in flow cytometry for detecting CXCR-1 present on human blood cells. It can also be used in immunohistochemistry (25 μg/mL) using frozen human tissue sections (spleen).

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

制备说明

Purified using protein G.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD02096157
NACRESNA.41

产品性质

质量水平100
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆42705.111, monoclonal
形式lyophilized powder
species reactivityhuman
technique(s)flow cytometry: 10 μg/mL using using human blood cells (10 μL diluted antibody/105-106 cells)
immunohistochemistry (frozen sections): 25 μg/mL using human tissue (speen)
neutralization: suitable
同位素/亚型IgG2a
储存温度−20℃
Gene Informationhuman ... IL8RA(3577)
mouse ... Il8ra(227288)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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