产品说明
一般描述
Albumin is the most copious protein in blood plasma. Liver produces human albumin.
应用
Albumin was used to test its effect on the in vitro bactericidal activity of cefditoren against penicillin-resistant Streptococcus pneumonia. It has been clinically used in serious and often life-threatening conditions, such as shock and blood loss due to trauma, burns, and surgery.
Albumin was used to study albumin-induced apoptosis in proximal tubule cells. It was also used in cell adhesion molecules and surface treatment studies.
生化/生理作用
血清白蛋白可作为类固醇、脂肪酸和甲状腺激素的载体蛋白,对调节血液的胶体渗透压至关重要。研究还发现白蛋白可结合外源物质,特别是药物(例如布洛芬、华法林),并强烈影响其药代动力学。导致白蛋白氧化还原状态变化的氧化应激对其生理功能具有广泛的影响。
Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin is also seen to bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influences their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has varied effects on its physiological function.
其他说明
查看更多关于 人血清白蛋白的信息。
基本信息
EC 号 | 274-272-6 |
MDL编号 | MFCD00081418 |
eCl@ss | 42010201 |
NACRES | NA.25 |
产品性质
质量水平 | 200 |
生物来源 | human |
测定 | ≥96% (agarose gel electrophoresis) |
形式 | lyophilized powder |
分子量 | monomer calculated mol wt 66478 Da |
杂质 | HIV I and HIVII, HCV and HBsAg, tested negative ≤1.0 EU/mg endotoxin |
溶解性 | H2O: soluble 50 mg/mL |
UniProt登记号 | P02768 |
储存温度 | 2-8℃ |
Gene Information | human ... ALB(213) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves |
Sigma-Aldrich