PTEN human

产品名称：

PTEN human
Phosphatidylinositol-3
PTEN
5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Mutated in multiple advanced cancers 1
Phosphatase and tensin homolog

产品介绍：

产品说明

生化/生理作用

PTEN, a tumor suppressor, has been implicated in a large number of human tumors and is conserved from humans to worms. Characterization of PTEN protein showed that it is a phosphatase that acts on proteins and on 3-phosphorylated phosphoinositides, and can therefore modulate signal-transduction pathways that involve lipid second messengers. Recent results indicate that at least part of its role is to regulate the activity of the serine/threonine kinase AKT/PKB, and thus influence cell survival signaling. Recombinant PTEN is purified by proprietary chromatographic techniques.

外形

Sterile filtered liquid at 100 μg/ml.

重悬

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

基本信息

MDL编号	MFCD03458266
NACRES	NA.32

产品性质

生物来源	human
重组	expressed in E. coli
测定	≥90%
形式	liquid
分子量	~86.0 kDa
包装	pkg of 5 μg
储存条件	avoid repeated freeze/thaw cycles
杂质	<0.1 EU/μg
NCBI登记号	P60484
运输	dry ice
储存温度	−70℃
Gene Information	human ... PTEN(5728)

安全信息

储存分类代码	10 - Combustible liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable