产品说明
一般描述
C16 Carnitine, also called as palmitoyl L-carnitine, is an endogenous acylcarnitine. Structurally, it contains Levocarnitine (L-carnitine) head group and 16 carbon saturated fatty acid tail. Palmitoyl L-carnitine is derived by reversible reaction of palmitoyl-CoA esters with carnitine. Palmitoyl L-carnitine is transported across the inner membrane by carnitine palmitoyl transferase II for β-oxidation.
应用
C16 Carnitine or palmitoyl L-carnitine has been used to study its influence on the glycine transporters activity.
生化/生理作用
C16 Carnitine has a potential to inhibit glycine transporter 2 (GlyT2). It acts as a key energy donor for β-oxidation. Palmitoyl carnitine activates the Ca2+ release channel of skeletal muscle sarcoplasmic reticulum. Elevated levels of palmitoyl L-carnitine due to palmitoyl transferase II deficiency causes autosomal recessive disorder of energy metabolism, which primarily affects skeletal muscle.
包装
5 mL Amber Glass Screw Cap Vial (870851P-5mg)
基本信息
经验(实验)分子式 | C23H45NO4 |
分子量 | 399.61 |
NACRES | NA.25 |
产品性质
形式 | powder |
包装 | pkg of 1 × 5 mg (870851P-5mg) |
manufacturer/tradename | Avanti Polar Lipids 870851P |
运输 | dry ice |
储存温度 | −20℃ |
SMILES string | C[N+](C)(C)C[C@H](OC(CCCCCCCCCCCCCCC)=O)CC([O-])=O |
InChI | 1S/C23H45NO4/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(27)28-21(19-22(25)26)20-24(2,3)4/h21H,5-20H2,1-4H3 |
InChI key | XOMRRQXKHMYMOC-UHFFFAOYSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
Sigma-Aldrich