产品说明
一般描述
α-Lactalbumin is an important whey protein in cow′s milk, and is also present in the milk of many other mammalian species. In primates, α-lactalbumin expression is upregulated in response to the hormone prolactin and increases the production of lactose. α-Lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and β-1,4-galactosyltransferase (β4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transferring galactose moieties to glucose. As a monomer, α-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. When formed into a complex with Gal-T1, a galactosyltransferase, α-lactalbumin, enhances the enzyme′s affinity for glucose by about 1000 times, and inhibits the ability to polymerize multiple galactose units. This gives rise to a pathway for forming lactose by converting Gal-TI to Lactose synthase.
外形
Lyophilized from de-ionized water.
重悬
Use deionized water
基本信息
NACRES | NA.32 |
产品性质
生物来源 | human milk |
测定 | ≥95% (SDS-PAGE) |
形式 | lyophilized |
分子量 | 14 kDa |
包装 | pkg of 5 mg |
UniProt登记号 | P00709 |
运输 | wet ice |
储存温度 | 2-8℃ |
Gene Information | human ... LYZL7(3906) |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich