N-(6-氧代-5,6-二氢菲啶-2-基)-(N,N-二甲基氨基)乙酰胺盐酸盐

产品名称：

344458-15-7
PJ-34 hydrochloride hydrate
PARP Inhibitor VIII
PJ 34 HCl
N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-(N,N-dimethylamino)acetamide hydrochloride
PJ-34 盐酸盐水合物
N-(6-氧代-5,6-二氢菲啶-2-基)-(N,N-二甲基氨基)乙酰胺盐酸盐

产品介绍：

产品说明

应用

PJ-34 hydrochloride hydrate has been used:

as a poly(ADP-ribose) polymerase (PARP) inhibitor 1 in rats to test the effect of PAPR1 in neuropathic pain
as a component of protein extraction buffer to enable visualization of the high-molecular-weight smear of PARylated proteins in various cell samples
as PARP inhibitor in murine MLE-12 epithelial cell line

包装

5 mg in glass bottle

生化/生理作用

PJ-34 is a prototypic poly(ADP-ribose) polymerase 1 (PARP-1) inhibitor.
PJ-34是一种强效聚(ADP-核糖)聚合酶(PARP)抑制剂。

基本信息

经验(实验)分子式	C₁₇H₁₇N₃O₂ · HCl · xH₂O
分子量	331.80 (anhydrous basis)
PubChem化学物质编号	24898531
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to yellow
溶解性	H₂O: 22 mg/mL
SMILES string	Cl[H].[H]O[H].CN(C)CC(=O)Nc1ccc2NC(=O)c3ccccc3-c2c1
InChI	1S/C17H17N3O2.ClH.H2O/c1-20(2)10-16(21)18-11-7-8-15-14(9-11)12-5-3-4-6-13(12)17(22)19-15;;/h3-9H,10H2,1-2H3,(H,18,21)(H,19,22);1H;1H2
InChI key	YCALIZUKAFUQCH-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)

PJ-34 hydrochloride hydrate

PJ-34 盐酸盐 水合物

PJ-34 盐酸盐水合物