产品说明
一般描述
Fludarabine is a purine analog included in the category of DNA-damaging drugs with well-known efficacy in B-cell chronic lymphocytic leukemia (B-CLL).
生化/生理作用
Fludarabine represses DNA replication and suppresses the nucleotide metabolism by inhibiting the enzyme ribonucleotide reductase.
基本信息
经验(实验)分子式 | C10H13FN5O7P |
分子量 | 365.21 |
NACRES | NA.85 |
产品性质
形式 | powder |
质量水平 | 200 |
颜色 | white |
溶解性 | DMSO: 1 mg/mL |
作用机制 | DNA synthesis | interferes |
抗生素抗菌谱 | neoplastics |
储存温度 | −20℃ |
InChI | 1S/C10H13FN5O7P/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(18)5(17)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,17-18H,1H2,(H2,12,14,15)(H2,19,20,21) |
InChI key | GIUYCYHIANZCFB-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H341 - H361d |
预防措施声明 | P201 - P202 - P280 - P308 + P313 - P405 - P501 |
危险分类 | Muta. 2 - Repr. 2 |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |