产品说明
一般描述
Fludarabine is a purine analog included in the category of DNA-damaging drugs with well-known efficacy in B-cell chronic lymphocytic leukemia (B-CLL).
生化/生理作用
Fludarabine represses DNA replication and suppresses the nucleotide metabolism by inhibiting the enzyme ribonucleotide reductase.
基本信息
| 经验(实验)分子式 | C10H13FN5O7P |
| 分子量 | 365.21 |
| NACRES | NA.85 |
产品性质
| 形式 | powder |
| 质量水平 | 200 |
| 颜色 | white |
| 溶解性 | DMSO: 1 mg/mL |
| 作用机制 | DNA synthesis | interferes |
| 抗生素抗菌谱 | neoplastics |
| 储存温度 | −20℃ |
| InChI | 1S/C10H13FN5O7P/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(18)5(17)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,17-18H,1H2,(H2,12,14,15)(H2,19,20,21) |
| InChI key | GIUYCYHIANZCFB-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H341 - H361d |
| 预防措施声明 | P201 - P202 - P280 - P308 + P313 - P405 - P501 |
| 危险分类 | Muta. 2 - Repr. 2 |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
