产品说明
一般描述
O-Desmethyl gefitinib is a major active metabolite of gefitinib. It is a potent EGFR (erbB1/HER1) inhibitor (IC50 = 36 nM). Gefitinib is metabolized by CYP2D6 to O-Desmethyl gefitinib. Gefitinib is an EGFR inhibitor that is used to treat some types of cancers.
应用
Metabolomics research
基本信息
| 经验(实验)分子式 | C21H22ClFN4O3 |
| 分子量 | 432.88 |
产品性质
| 质量水平 | 100 |
| 生物来源 | synthetic |
| 等级 | research grade |
| 测定 | ≥95% |
| 形式 | solid |
| technique(s) | HPLC: suitable |
| 颜色 | light yellow to yellow |
| 储存温度 | −20℃ |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H302 - H315 - H319 - H335 |
| 预防措施声明 | P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
