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5α,6β-dihydroxycholestanol

5α,6β-dihydroxycholestanol

品牌
Avanti
CAS
1253-84-5
货号
700054P
规格纯度
Cholestane-3β,5α,6β-triol, powder
参考价格
1002.37 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
1253-84-5
5α,6β-dihydroxycholestanol
3β,5α,6β-trihydroxycholestane
产品介绍:

产品说明

一般描述

5α,6β-dihydroxycholestanol is a structural derivative of cholesterol. It is produced by the low-density lipoprotein oxidation (LDL) and is a cholesterol autooxidation product. 5α,6β-dihydroxycholestanol is an abundant oxysterol.

应用

5α,6β-dihydroxycholestanol has been used as a cholesterol oxidation product in reversed phase chromatography (RP-HPLC) and mass spectroscopy analysis. It may be used as an internal standard in tandem mass spectrometry (MS/MS analysis) of plasma samples.

生化/生理作用

5α,6β-dihydroxycholestanol (5α,6α-diOH-Chol) or cholestan-3β,5α,6β-triol (C-triol) levels are elevated along with 7-ketocholesterol in Niemann-Pick type C (NP-C) disease and is a key biomarkers for detection. It exhibits neuroprotective functionality during central nervous system (CNS) ischemia.

包装

5 mL Amber Glass Screw Cap Vial (700054P-25mg)
5 mL Amber Glass Screw Cap Vial (700054P-5mg)

基本信息

经验(实验)分子式C27H48O3
分子量420.67
NACRESNA.25

产品性质

测定>99% (TLC)
形式powder
包装pkg of 1 × 25 mg (700054P-25mg)
pkg of 1 × 5 mg (700054P-5mg)
manufacturer/tradenameAvanti Polar Lipids 700054P
运输dry ice
储存温度−20℃
InChI1S/C27H48O3/c1-17(2)7-6-8-18(3)21-9-10-22-20-15-24(29)27(30)16-19(28)11-14-26(27,5)23(20)12-13-25(21,22)4/h17-24,28-30H,6-16H2,1-5H3/t18-,19+,20+,21-,22+,23+,24-,25-,26-,27+/m1/s1
InChI keyYMMFNKXZULYSOQ-RUXQDQFYSA-N

安全信息

危险声明H413
预防措施声明P273 - P501
危险分类Aquatic Chronic 4
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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