BAY-678

产品名称：

675103-36-3
BAY-678
5-{(4R)-5-Acetyl-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrimidin-4-yl}pyridine-2-carbonitrile
2-Pyridinecarbonitrile, 5-[(4R)-5-acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

BAY-678 is an orally available, highly potent and selective inhibitor of human neutrophil elastase (HNE). For full characterization details, please visit the BAY-678 probe summary on the Structural Genomics Consortium (SGC) website.

BAY-677 is used as a negative control and is available from Sigma. To learn more about and purchase BAY-677, click here.

To learn about other SGC chemical probes for protein targets, visit sigma.com/sgc

特点和优势

BAY-678 is a chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC chemical probes, visit sigma.com/SGC.

基本信息

经验(实验)分子式	C₂₀H₁₅F₃N₄O₂
分子量	400.35
MDL编号	MFCD29924806
PubChem化学物质编号	329825966
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
旋光性	[α]/D +21 to +29°, c = 0.5 in methanol
颜色	white to light brown
溶解性	DMSO: 20 mg/mL, clear
储存温度	2-8℃
SMILES string	CC(N1C2=CC=CC(C(F)(F)F)=C2)=C(C(C)=O)[C@@H](C3=CN=C(C#N)C=C3)NC1=O
InChI	1S/C20H15F3N4O2/c1-11-17(12(2)28)18(13-6-7-15(9-24)25-10-13)26-19(29)27(11)16-5-3-4-14(8-16)20(21,22)23/h3-8,10,18H,1-2H3,(H,26,29)/t18-/m1/s1
InChI key	PGIVGIFOWOVINL-GOSISDBHSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable