BDT001

产品名称：

823837-22-5
BDT001
N-(5-Chloro-2-hydroxyphenyl)-3-(piperidin-1-ylsulfonyl) benzamide

产品介绍：

产品说明

生化/生理作用

BDT001 is a selective negative allosteric modulator of Flt-3 receptor tyrosine kinase. It showed minimal binding to 25 diverse RTKs and 49 intracellular kinases. In primary cultures of adult DRG neurons, BDT001 reversed the potentiation of capsaicin-induced TRPV1 activation by FL, with a maximal effect at 1 μM. In a mouse study BDT001 alleviated nerve injury-induced peripheral neuropathic pain but had no effect on nociception in non-injured animals.

基本信息

经验(实验)分子式	C₁₈H₁₉ClN₂O₄S
分子量	394.87

产品性质

测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	2-8℃
SMILES string	OC1=CC=C(C=C1NC(C2=CC=CC(S(N3CCCCC3)(=O)=O)=C2)=O)Cl

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable