产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
BEPP is a double-strand RNA-dependent protein kinase (PKR) activator. The double-strand RNA (dsRNA)-dependent protein kinase is a ubiquitously expressed serine threonine kinase, inducible by interferon γ. PRK is involved in several curtail cellular regulations including phosphorylation of eIF2α (which leads to inhibition of protein synthesis and eliciting antivirus and antitumor activities), modulating activities of eIF2α, NF-κB, ATF-3, and p53. BEPP also inhibits the growth of a human lung cancer cell line overexpressing PKR.
基本信息
| 经验(实验)分子式 | C23H23N3O2 HCl |
| 分子量 | 409.91 |
| MDL编号 | MFCD00964481 |
| PubChem化学物质编号 | 329773209 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 储存条件 | desiccated |
| 颜色 | white to off-white |
| 溶解性 | DMSO: >10 mg/mL |
| 储存温度 | 2-8℃ |
| SMILES string | Cl.OC(COc1ccccc1)CN2C(=N)N(Cc3ccccc3)c4ccccc24 |
| InChI | 1S/C23H23N3O2.ClH/c24-23-25(15-18-9-3-1-4-10-18)21-13-7-8-14-22(21)26(23)16-19(27)17-28-20-11-5-2-6-12-20;/h1-14,19,24,27H,15-17H2;1H |
| InChI key | KDMXJFUGIDGZQL-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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