产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
CP-424,174 is a cytokine release inhibitory drugs (CRID) that inhibits the post-translational processing and secretion of IL-1b in response to LPS and ATP in human monocytes. It is quite possible that similarly to CP-456,773 (termed CRID3), CP-424,174 inhibits both NLRP3 and AIM2 inflammasomes by preventing ASC oligomerisation.
法律信息
Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
基本信息
经验(实验)分子式 | C22H29ClN2O4S |
分子量 | 452.99 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
manufacturer/tradename | Pfizer® |
颜色 | white to beige |
溶解性 | DMSO: 20 mg/mL, clear |
创始人 | Pfizer |
储存温度 | room temp |
SMILES string | CC(O)(C)C1=CC(S(=O)(NC(NC2=C(C(C)C)C=C(Cl)C=C2C(C)C)=O)=O)=CC=C1 |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich