白桦脂酸

产品名称：

472-15-1
Betulinic Acid
Mairin
Lupatic acid
3β-Hydroxy-20(29)-lupaene-28-oic Acid
白桦脂酸
卢帕酸
丁子香萜

产品介绍：

产品说明

一般描述

Betulinic acid (BetA) is a natural product mostly sourced from the birch tree (Betula spp.). This pentacyclic lupanetype triterpenoid is also associated with other species such as Syzygium spp., Diospyros spp., Ziziphus spp., and Paeonia spp..

应用

Betulinic acid (BetA) has been used:

to test its effects as an antiviral agent against Dengue virus (DENV)
as a sterol regulatory element-binding protein (SREBP) inhibitor to repress the lipid metabolism and proliferation of clear cell renal cell carcinoma (ccRCC) cells
as a treatment to test its anti-tumor properties for cell viability and apoptotic cell death assays in multiple myeloma models

包装

5, 25 mg in glass bottle

生化/生理作用

Betulinic acid displays many biological and pharmacological properties such as anticancer, anti-inflammatory, anti-bacterial, anti-human immunodeficiency virus (HIV), and anti-malarial properties.
桦木酸是一种五环三萜类化合物，通过p53 和 CD95 非依赖性机制直接激活细胞凋亡的线粒体途径选择性地诱导肿瘤细胞凋亡。

基本信息

经验(实验)分子式	C₃₀H₄₈O₃
分子量	456.70
EC 号	207-448-8
MDL编号	MFCD00009619
PubChem化学物质编号	329773146
NACRES	NA.25

产品性质

质量水平	100
测定	≥98% (HPLC)
mp	295-298 ℃ (dec.) (lit.)
储存温度	2-8℃
SMILES string	CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)C(O)=O
InChI	1S/C30H48O3/c1-18(2)19-10-15-30(25(32)33)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h19-24,31H,1,8-17H2,2-7H3,(H,32,33)/t19-,20+,21-,22+,23-,24+,27-,28+,29+,30-/m0/s1
InChI key	QGJZLNKBHJESQX-FZFNOLFKSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable