GSK334429 hydrochloride

产品名称：

799558-94-4
GSK334429 hydrochloride
1-(1-Methylethyl)-4-((1-(6-(trifluoromethyl)-3-pyridinyl)-4-piperidinyl)carbonyl)hexahydro-1H-1,4-diazepine hydrochloride

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

GSK334429 is a selective histamine H3 receptor antagonist. H3 antagonists increase the release of brain histamine, ACh, NE and DA neurotransmitters that modulate cognitive processes. Studies look at their analgesic efffects including efficacy for neuropathic pain.

特点和优势

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

其他说明

Store desiccated; dry room.

基本信息

经验(实验)分子式	C₂₀H₂₉F₃N₄O · xHCl
分子量	398.47 (free base basis)
MDL编号	MFCD22666404
PubChem化学物质编号	329825449
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
储存条件	desiccated
颜色	white to beige
溶解性	H₂O: 5 mg/mL (clear solution)
储存温度	2-8℃
SMILES string	Cl.CC(C)N1CCCN(CC1)C(=O)C2CCN(CC2)c3ccc(nc3)C(F)(F)F
InChI	1S/C20H29F3N4O.ClH/c1-15(2)25-8-3-9-27(13-12-25)19(28)16-6-10-26(11-7-16)17-4-5-18(24-14-17)20(21,22)23;/h4-5,14-16H,3,6-13H2,1-2H3;1H
InChI key	RCZVWLOXPFGZDD-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable