α-Cyano-(3-methoxy-4-hydroxy-5-iodocinnamoyl)-(3′,4′-dihydroxyphenyl)ketone

产品名称：

I-OMe-Tyrphostin AG 538
α-Cyano-(3-methoxy-4-hydroxy-5-iodocinnamoyl)-(3′,4′-dihydroxyphenyl)ketone
I-OMe-AG 538

产品介绍：

产品说明

应用

I-OMe-Tyrphostin AG 538 has been used as a cell signaling inhibitor in PC-1 cell lines. It has also been used in high throughput screening assays for IGF1R inhibitors.

包装

5 mg in glass bottle

生化/生理作用

Insulin growth factor 1 (IGF-1) receptor protein tyrosine kinase inhibitor.

特点和优势

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制备说明

I-OMe-Tyrphostin AG 538 is soluble in DMSO at 50 mg/ml.

基本信息

经验(实验)分子式	C₁₇H₁₂INO₅
分子量	437.19
MDL编号	MFCD03453582
PubChem化学物质编号	24278758
NACRES	NA.77

产品性质

质量水平	100
形式	solid
溶解性	DMSO: 50 mg/mL
储存温度	−20℃
SMILES string	COc1cc(cc(I)c1O)\C=C(/C#N)C(=O)c2ccc(O)c(O)c2
InChI	1S/C17H12INO5/c1-24-15-6-9(5-12(18)17(15)23)4-11(8-19)16(22)10-2-3-13(20)14(21)7-10/h2-7,20-21,23H,1H3/b11-4+
InChI key	HSRMHXWCTRFVHK-NYYWCZLTSA-N
Gene Information	human ... IGF1(3479), IGF1R(3480)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)