产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
Imperatorin is an important bioactive furanocoumarin. It is used to treat neurodegenerative diseases. It possesses anticancer, antibacterial, anti-inflammatory and HIV replication-inhibiting activities. Imperatorin serves as an inhibitor of acetylcholinesterase (AChE) and may help in treating Alzheimer′s disease (AD) and Parkinson′s disease (PD).
Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
特点和优势
This compound is featured on the MAPKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
基本信息
经验(实验)分子式 | C16H14O4 |
分子量 | 270.28 |
EC 号 | 207-581-1 |
MDL编号 | MFCD00016881 |
PubChem化学物质编号 | 329815395 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | off-white to light brown |
溶解性 | DMSO: ≥5 mg/mL |
储存温度 | 2-8℃ |
SMILES string | C\C(C)=C\COc1c2OC(=O)C=Cc2cc3ccoc13 |
InChI | 1S/C16H14O4/c1-10(2)5-7-19-16-14-12(6-8-18-14)9-11-3-4-13(17)20-15(11)16/h3-6,8-9H,7H2,1-2H3 |
InChI key | OLOOJGVNMBJLLR-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 |
预防措施声明 | P301 + P312 + P330 |
危险分类 | Acute Tox. 4 Oral |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich