NCX 4016

产品名称：

175033-36-0
NCX 4016
NCX-4016
2-Acetoxybenzoic acid 3-nitrooxymethylphenyl ester
Nitroaspirin
3-(Nitroxymethyl)phenyl 2-acetoxybenzoate
2-(Acetyloxy)-benzoic acid 3-[(nitrooxy)methyl]phenyl ester

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

NCX 4016 (nitroaspirin) is nitroderivative of aspirin that combines cyclooxygenase inhibitor with an NO donor. NCX 4016 improves postischemic ventricular dysfunction and to reduce myocardial infarct size in rabbit.
NCX-4016 can prevent the progression of cisplatin-resistant human ovarian cancer xenografts in mice. It can also regulate the expression of B-cell lymphoma 2 (Bcl-2) proteins in ovarian cancer cells. Hence, NCX-4016 is considered a promising therapeutic option against carcinoma.

基本信息

经验(实验)分子式	C₁₆H₁₃NO₇
分子量	331.28
MDL编号	MFCD01939436
PubChem化学物质编号	329826004
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 25 mg/mL, clear
储存温度	−20℃
SMILES string	CC(OC1=CC=CC=C1C(OC2=CC(CO[N+]([O-])=O)=CC=C2)=O)=O
InChI	1S/C16H13NO7/c1-11(18)23-15-8-3-2-7-14(15)16(19)24-13-6-4-5-12(9-13)10-22-17(20)21/h2-9H,10H2,1H3
InChI key	IOJUJUOXKXMJNF-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable