PF-06745268

产品名称：

1812190-38-7
PF-06745268
2-[[(1aS,7bS)-1a,2-Dihydro-2,2-dimethyl-6-(trifluoromethyl)benzo[b]cyclopropa[d]pyran-7b(1H)-yl]methyl]-3,4-dihydro-7-(4-methyl-1H-imidazol-1-yl)-2H-pyrido[1,2-a]pyrazine-1,6-dione

产品介绍：

产品说明

生化/生理作用

PF-06745268 is an orally available, brain penetrant, potent and selective γ-secretase modulator. PF-06745268 induces robust and sustained reduction of brain amyloid-β42 (Aβ42) in rats.

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.

基本信息

经验(实验)分子式	C₂₆H₂₅F₃N₄O₃
分子量	498.50
NACRES	NA.77

产品性质

测定	≥98% (HPLC)
形式	powder
旋光性	[α]/D -13 to -17°, c = 1.0 in methanol
manufacturer/tradename	Pfizer^®
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
创始人	Pfizer
储存温度	2-8℃
SMILES string	O=C1C(N2C=C(N=C2)C)=CC=C3N1CCN(C[C@@]4(C5)[C@@]5([H])C(C)(C)OC6=C4C=C(C(F)(F)F)C=C6)C3=O

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable