产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
The acyclic nucleotide 9-(2-phosphonylmethoxyethyl)guanine (PMEG) forms an active phosphorylated metabolite, PMEG diphosphate (PMEGpp), in cells and causes cytotoxicity in dividing cells due to potent inhibition of the nuclear DNA polymerases resulting in inhibition of DNA synthesis and/or DNA repair.
基本信息
| 经验(实验)分子式 | C8H12N5O5P · xH2O |
| 分子量 | 289.19 (anhydrous basis) |
| MDL编号 | MFCD19443863 |
| PubChem化学物质编号 | 329817932 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 储存条件 | desiccated |
| 颜色 | white to off-white |
| 溶解性 | DMSO: ≥5 mg/mL |
| 储存温度 | 2-8℃ |
| SMILES string | O.NC1=Nc2c(ncn2CCOCP(O)(O)=O)C(=O)N1 |
| InChI | 1S/C8H12N5O5P.H2O/c9-8-11-6-5(7(14)12-8)10-3-13(6)1-2-18-4-19(15,16)17;/h3H,1-2,4H2,(H2,15,16,17)(H3,9,11,12,14);1H2 |
| InChI key | BDVQXHFCXJXVND-UHFFFAOYSA-N |
Sigma-Aldrich
m.cnreagent.com
