Pimelic Diphenylamide 106

产品名称：

937039-45-7
Pimelic Diphenylamide 106
N1-(2-Aminophenyl)-N7-(4-methylphenyl)-heptanediamide
Compound 106
RGFA 8
TC-H 106
Inhibitor 106

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Pimelic diphenylamides has the ability to enhance the expression of the frataxin gene in lymphocytes from Friedreich ataxia patients.
106 is a Class I HDAC inhibitor, demonstrating no activity against class II HDACs. It is a slow, tight-binding inhibitor of HDACs 1, 2, and 3, with a preference toward HDAC3 with Ki of 14 nM, 15 times lower than the Ki for HDAC1.

基本信息

经验(实验)分子式	C₂₀H₂₅N₃O₂
分子量	339.43
MDL编号	MFCD17010287
PubChem化学物质编号	329825318
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: ≥15 mg/mL
储存温度	2-8℃
SMILES string	Cc1ccc(NC(=O)CCCCCC(=O)Nc2ccccc2N)cc1
InChI	1S/C20H25N3O2/c1-15-11-13-16(14-12-15)22-19(24)9-3-2-4-10-20(25)23-18-8-6-5-7-17(18)21/h5-8,11-14H,2-4,9-10,21H2,1H3,(H,22,24)(H,23,25)
InChI key	WTKBRPXPNAKVEQ-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable