产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
Pimelic diphenylamides has the ability to enhance the expression of the frataxin gene in lymphocytes from Friedreich ataxia patients.
106 is a Class I HDAC inhibitor, demonstrating no activity against class II HDACs. It is a slow, tight-binding inhibitor of HDACs 1, 2, and 3, with a preference toward HDAC3 with Ki of 14 nM, 15 times lower than the Ki for HDAC1.
基本信息
| 经验(实验)分子式 | C20H25N3O2 |
| 分子量 | 339.43 |
| MDL编号 | MFCD17010287 |
| PubChem化学物质编号 | 329825318 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to beige |
| 溶解性 | DMSO: ≥15 mg/mL |
| 储存温度 | 2-8℃ |
| SMILES string | Cc1ccc(NC(=O)CCCCCC(=O)Nc2ccccc2N)cc1 |
| InChI | 1S/C20H25N3O2/c1-15-11-13-16(14-12-15)22-19(24)9-3-2-4-10-20(25)23-18-8-6-5-7-17(18)21/h5-8,11-14H,2-4,9-10,21H2,1H3,(H,22,24)(H,23,25) |
| InChI key | WTKBRPXPNAKVEQ-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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