(±)-1,2-Bis(3,5-dioxopiperazinyl)propane

产品名称：

21416-67-1
Razoxane
ICRF 159
ICI 59118
NSC 129943
(±)-1,2-Bis(3,5-dioxopiperazinyl)propane
1,2-Bis(3,5-dioxo-1-piperazinyl)propane
Razoxin
4,4′-Propylenebis(2,6-piperazinedione)
(±)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane
Tepirone
Troxozone

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Razoxane is clinically active against angiogenesis and metastasis. Razoxane specifically inhibits topoisomerase II without inducing DNA strand breaks (topo II catalytic inhibitor). It is an antimitotic agent with immunosuppressive properties. Razoxane inhibits blood-borne and lymphatic metastases in different experimental models. Studies have shown that razoxane inhibits specifically the vasculogenic mimicry of B16F10 melanoma cells.

基本信息

经验(实验)分子式	C₁₁H₁₆N₄O₄
分子量	268.27
EC 号	244-379-2
MDL编号	MFCD00430424
PubChem化学物质编号	329824039
NACRES	NA.77

产品性质

质量水平	100
测定	>98% (HPLC)
形式	solid
溶解性	DMSO: 40 mg/mL
储存温度	room temp
SMILES string	CC(CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2
InChI	1S/C11H16N4O4/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19)
InChI key	BMKDZUISNHGIBY-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable