2′-Hydroxy-2,4,4′,5,6′-pentamethoxychalcone

产品名称：

73694-15-2
Rubone
2′-Hydroxy-2,4,4′,5,6′-pentamethoxychalcone
(2E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(2,4,5-trimethoxyphenyl)-2-propen-1-one

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Rubone has strong anticancer activity. Rubone and paclitaxel (PTX) combination therapy retarded cancer cell growth, migration and cancer stem-like cells (CSC) population growth.
Rubone is a miR34a modulator that specifically restores miR34a in hepatocellular carcinoma cells with wild-type or mutated p53. Rubone potently inhibits growth of hepatocellular carcinoma in a mouse xenograft model. Rubone does not effect the growth of nontumorigenic human hepatocytes.
Rubone is a miR34a modulator that specifically restores miR34a in hepatocellular carcinoma cells.

基本信息

经验(实验)分子式	C₂₀H₂₂O₇
分子量	374.38
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
储存条件	desiccated
颜色	yellow to orange
溶解性	DMSO: 2 mg/mL, clear (warmed)
储存温度	2-8℃

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable