S-2E

产品名称：

155730-92-0
S-2E
(S)-(+)-4-[1-(4-tert-Butylphenyl)-2-oxo-pyrrolidin-4-yl]methoxybenzoic acid

产品介绍：

产品说明

应用

S-2E may be used in cell signaling studies.

包装

5, 25 mg in glass bottle
Shipped ambient under nitrogen.

生化/生理作用

HMG-CoA reductase and acetyl-CoA carboxylase inhibitor. In the liver, S-2E is converted into its active metabolite, S-2E-CoA. S-2E-CoA noncompetitively inhibited the enzymatic activities of both 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductase and acetyl-CoA carboxylase at K(i)=18.11 microM and K(i)=69.2 microM, respectively.

基本信息

经验(实验)分子式	C₂₂H₂₅NO₄
分子量	367.44
MDL编号	MFCD06407742
PubChem化学物质编号	24724620
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white
溶解性	DMSO: 11 mg/mL H₂O: insoluble
储存温度	−20℃
SMILES string	CC(C)(C)c1ccc(cc1)N2C[C@@H](COc3ccc(cc3)C(O)=O)CC2=O
InChI	1S/C22H25NO4/c1-22(2,3)17-6-8-18(9-7-17)23-13-15(12-20(23)24)14-27-19-10-4-16(5-11-19)21(25)26/h4-11,15H,12-14H2,1-3H3,(H,25,26)/t15-/m0/s1
InChI key	YZADMDZNVOBYGR-HNNXBMFYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)