产品说明
应用
Telbivudine has been used to explore the mechanisms of telbivudine (LdT) induced creatine kinase (CK) elevation.
包装
5, 25 mg in glass bottle
生化/生理作用
Telbivudine is a nucleoside analog that is widely used to treat hepatitis B virus (HBV) infection.
Telbivudine is a synthetic molecule containing β-L-configuration. Telbivudine improves the estimated glomerular filtration rate (eGFR) in response to chronic hepatitis B (CHB). It prevents perinatal transmission and enhances the hepatitis B e antigen (HBeAg) seroconversion. It is also known to cause side effects such as creatine kinase (CK) elevation and fatal rhabdomyolysis.
基本信息
| 经验(实验)分子式 | C10H14N2O5 |
| 分子量 | 242.23 |
| MDL编号 | MFCD02683612 |
| PubChem化学物质编号 | 329825300 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 旋光性 | [α]/D -15 to -22°, c = 1 in H2O |
| 颜色 | white to beige |
| 溶解性 | H2O: 10 mg/mL (clear solution) |
| 储存温度 | 2-8℃ |
| SMILES string | CC1=CN([C@@H]2C[C@@H](O)[C@H](CO)O2)C(=O)NC1=O |
| InChI | 1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m1/s1 |
| InChI key | IQFYYKKMVGJFEH-CSMHCCOUSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H302 |
| 危险分类 | Acute Tox. 4 Oral |
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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