UCL 1684 ditrifluoroacetate hydrate

产品名称：

201147-19-5
UCL 1684 ditrifluoroacetate hydrate
6,12,19,20,25,26-hexahydro- 5,27:13,18:21,24-Trietheno-11,7-metheno-7H-dibenzo[b,m][1,5,12,16]tetraazacyclotricosine-5,13-diium ditrifluoroacetate hydrate

产品介绍：

产品说明

应用

UCL 1684 ditrifluoroacetate hydrate has been used for analyzing the mechanism for ammonium-mediated displacement of the protonated analyte from analyte-trifluoroacetic acid (TFA) ion-pair. UCL 1684 has also been used as a potassium channel inhibitor to study CNP (C-type natriuretic peptide)-induced relaxations in pig coronary arteries.

包装

5, 25 mg in glass bottle

生化/生理作用

UCL 1684 is a potent non-peptide blocker of the apamin-sensitive Ca²⁺-activated K⁺channel. It comprises two quinolinium rings and is similar to apamin arginine residue. UCL 1684 inhibits calcium-activated K current (Kslow) and modulates islet β-cell.

特点和优势

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

制备说明

UCL 1684 ditrifluoroacetate hydrate is soluble in water at 10 mg/ml.

基本信息

线性分子式	(C₃₄H₃₀N₄)²⁺ · (C₂F₃O₂^-)₂ · xH₂O
分子量	720.66 (anhydrous basis)
PubChem化学物质编号	24900684
NACRES	NA.77

产品性质

质量水平	100
颜色	white to off-white
溶解性	DMSO: 10 mg/mL
SMILES string	[H]O[H].FC(F)(C(O)=O)F.FC(F)(C(O)=O)F.C12=CC=CC=C1C(NCC3=CC=C(CNC4=CC=[N+](C5)C6=C4C=CC=C6)C=C3)=CC=[N+]2CC7=CC=CC5=C7
InChI	1S/C34H28N4.2C3H3F3O2.H2O/c1-3-10-33-29(8-1)31-16-18-37(33)23-27-6-5-7-28(20-27)24-38-19-17-32(30-9-2-4-11-34(30)38)36-22-26-14-12-25(13-15-26)21-35-31;24-3(5,6)1-2(7)8;/h1-20H,21-24H2;21H2,(H,7,8);1H2/b35-31+,36-32+;;;
InChI key	YROHEYZVNZITJN-DDVHGCDCSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)