UM-164 trifluoroacetate salt

产品名称：

UM-164 trifluoroacetate salt
2-[[6-[4-(2-Hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-N-[2-methyl-5-[[3-(trifluoromethyl)benzoyl]amino]phenyl]-5-thiazolecarboxamide trifluoroacetate salt

产品介绍：

产品说明

生化/生理作用

UM-164 is a potent dual c-Src/p38 kinase inhibitor that exhibits potent anti-TNBC activity in xenograft models. UM-164 inhibits p38 kinase and binds to an inactive c-Src conformation. UM-164 has a high therapeutic index in vivo.

基本信息

经验(实验)分子式	C₃₀H₃₁F₃N₈O₃S · xC₂HF₃O₂
分子量	640.68 (free base basis)

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	H₂O: 10 mg/mL, clear
储存温度	2-8℃
SMILES string	OCCN(CC1)CCN1C2=CC(NC3=NC=C(C(NC4=CC(NC(C5=CC(C(F)(F)F)=CC=C5)=O)=CC=C4C)=O)S3)=NC(C)=N2

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319
预防措施声明	P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable