Cyclohexylcarbamic acid 3′–carbamoyl–6–hydroxybiphenyl–3

产品名称：

1357160-72-5
URB937
Cyclohexylcarbamic acid 3′–carbamoyl–6–hydroxybiphenyl–3–yl ester

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

URB937 is a fatty acid amide hydrolase (FAAH) inhibitor that is actively excluded from the CNS by the membrane transporter ABCG2. The ED₅₀ for inhibition of FAAH activity in the brain is 200 times higher than inhibition of renal FAAH activity. In vivo administration of URB937 elevates anandamide levels in peripheral tissues, and attenuates acetic acid-induced writhing, hyperalgesia in a sciatic nerve ligation model, and pain and edema in carrageenan injected paws.

基本信息

经验(实验)分子式	C₂₀H₂₂N₂O₄
分子量	354.40
NACRES	NA.77

产品性质

质量水平	100
测定	≥95% (HPLC)
形式	powder (1:1 ratio of product to ethanol)
颜色	white to beige
溶解性	DMSO: 15 mg/mL, clear
储存温度	−20℃

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable