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Valdecoxib

伐地昔布

品牌
Sigma-Aldrich
CAS
181695-72-7
货号
PZ0179
规格纯度
≥98% (HPLC)
参考价格
1364.72 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
181695-72-7
Valdecoxib
4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide
伐地昔布
产品介绍:

产品说明

一般描述

Valdecoxib (VCX) is a diaryl substituted isoxazole compound. It comprises of sulfonyl propanamide and is a metabolite of parecoxib.

应用

Valdecoxib may be used: as cyclooxygenase-2 (COX-2) inhibitor in fibroblast cells, as an analyte for mass spectrometry analysis, as an standard in ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) for quantification of valdecoxib in plasma samples

包装

5, 25 mg in glass bottle

生化/生理作用

Valdecoxib is reported to elicit anti-inflammatory, analgesic and antipyretic functionality. It acts as a substrate for the liver enzyme cytochrome P450 2C9(CYP2C9) and cytochrome P450 3A4 (CYP3A4).
Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID), a cyclooxygenase-2 (COX-2) selective inhibitor.

其他说明

This compound was developed by Pfizer for Lipid Signaling research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.

基本信息

经验(实验)分子式C16H14N2O3S
分子量314.36
MDL编号MFCD00950568
PubChem化学物质编号329823753
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
manufacturer/tradenamePfizer®
颜色 white to off-white
溶解性DMSO: >25 mg/mL
创始人Pfizer
储存温度room temp
SMILES stringCc1onc(-c2ccccc2)c1-c3ccc(cc3)S(N)(=O)=O
InChI1S/C16H14N2O3S/c1-11-15(12-7-9-14(10-8-12)22(17,19)20)16(18-21-11)13-5-3-2-4-6-13/h2-10H,1H3,(H2,17,19,20)
InChI keyLNPDTQAFDNKSHK-UHFFFAOYSA-N
Gene Informationhuman ... PTGS2(5743)

安全信息

象形图GHS08GHS09
警示用语:Warning
危险声明H361d - H373 - H410
预防措施声明P201 - P202 - P260 - P273 - P280 - P308 + P313
危险分类Aquatic Chronic 1 - Repr. 2 - STOT RE 2
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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