ABT-491 hydrochloride

产品名称：

189689-94-9
ABT-491 hydrochloride
A-137491
4-Ethynyl-N,N-dimethyl-3-[3-fluoro-4-[(2-methyl-1H-imidazo-[4,5-c]pyridin-1-yl)methyl]benzoyl]-1H-indole-1-carboxamide hydrochloride

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Highly potent, selective and orally active platelet-activating factor (PAF) receptor antagonist. K_i = 0.6 nM in human platelets.

特点和优势

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
This compound is featured on the PAF Receptor page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式	C₂₈H₂₂N₅O₂F · HCl
分子量	515.97
MDL编号	MFCD00945301
PubChem化学物质编号	24724404
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
颜色	white to beige
mp	170-178 ℃ (lit.)
溶解性	H₂O: freely soluble 22 mg/mL
创始人	Abbott
储存温度	2-8℃
SMILES string	Cl[H].CN(C)C(=O)n1cc(C(=O)c2ccc(Cn3c(C)nc4cnccc34)c(F)c2)c5c(cccc15)C#C
InChI	1S/C28H22FN5O2.ClH/c1-5-18-7-6-8-25-26(18)21(16-34(25)28(36)32(3)4)27(35)19-9-10-20(22(29)13-19)15-33-17(2)31-23-14-30-12-11-24(23)33;/h1,6-14,16H,15H2,2-4H3;1H
InChI key	AWRGBOKANQBIBM-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)